The Dirichlet-multinomial (DM) distribution plays a fundamental role in modern statistical methodology development and application. Recently, the DM distribution and its variants have been used extensively to model multivariate count data generated by high-throughput sequencing technology in omics research due to its ability to accommodate the compositional structure of the...
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Methodology paper accepted in Biometrics
Infinite Hidden Markov Models for Multiple Multivariate Time Series with Missing Data
Congrats to Dr. Lauren Hoskovec for earning honorable mention in the ENVR Student Paper Competition for
the Joint Statistical Meetings 2021 for this work!
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Methodology paper accepted in Psychological Methods
Bayesian Continuous-Time Hidden Markov Models with Covariate Selection for Intensive Longitudinal Data with Measurement Error
Continuous-time hidden Markov models enable researchers to study the relations between risk factors and outcomes repeatedly measured at unbalanced, unequally spaced assessment times while accommodating measurement error. Despite extensive implementation of variable selection methods designed to identify potential relations in exploratory settings for hypothesis generation, currently none have been applied...
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Methodology paper accepted at Annals of Applied Statistics
A Bayesian Time-Varying Effect Model for Behavioral mHealth Data
The integration of mobile health (mHealth) devices into behavioral health research has fundamentally changed the way researchers and interventionalists are able to collect data as well as deploy and evaluate intervention strategies. In these studies, researchers often collect intensive longitudinal data (ILD) using ecological momentary assessment methods, which aim to...
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Methodology paper accepted at Annals of Applied Statistics
A Bayesian model of microbiome data for simultaneous identification of covariate association and prediction of phenotypic outcomes
One of the major research questions regarding human microbiome studies is the feasibility of designing interventions that modulate the composition of the microbiome to promote health and cure disease. This requires extensive understanding of the modulating factors of the microbiome, such as dietary intake, as well as the relation between...
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